Elena Nosyreva, Ph.D.
Instructor

Download Curriculum Vitae

EDUCATION

MSc in Physiology, 1976, College of Biology, St. Petersburg State University, St..Petersburg, Russia

PhD in Cytology, 1980, Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia.

SUMMARY OF PROFESSIONAL EXPERIENCE

Vast research experience in physiology, neurobiology and signal transduction, wide spectrum of electrophysiological, cellular biological and biochemical skills including expertise in electrophysiology: voltage clamp technique, patch clamp technique, single channel recordings of reconstituted proteins in bilayers, extracellular recordings from mammalian brain slices and insect and mammalian neuromuscular junctions. Experience in protein expression and purification. Significant experience in molecular biology techniques. Extensive cell culture experience

POSITIONS HELD

2002- present Instructor, Department of Neuroscience, UT Southwestern

1999- 2002 Postdoctoral Fellow, Instructor, Department of Physiology, UT Southwestern

1990- 1999 Senior Scientist, Ph.D. in the Laboratory of Neuroreceptors and Neuroregulators, the Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, RAS, Moscow, Russia

1981-1988 Scientist, PhD in the Lab of Ionic channels, Institute of Cytology RAS, St. Petersburg, Russia

 

Undergraduate

Saint Petersburg State Univers (1976), Physiology

Graduate School

Saint Petersburg State Univers (1976), Physiology

Graduate School

Institute of Cytology Ras (1979), Science

Featured Publications

Developmental switch in synaptic mechanisms of hippocampal mGluR dependent long-term depression

Nosyreva E., Huber K, J. Neuroscience 2005 25 (11): 2992-3001

The high-affinity calcium-calmodulin-binding site does not play a role in the modulation of type 1 inositol (1,4,5)-trisphosphate receptor function by

E. Nosyreva, T. Miyakawa, Z. Wang, L., L. Glouchankova, A. Mizushima, M. Iino and I. Bezprozvanny Biochem.J., 2002 365 659-667.

Age dependence of the rapid antidepressant and synaptic effects of acute NMDA receptor blockade.

Nosyreva E, Autry AE, Kavalali ET, Monteggia LM Front Mol Neurosci 2014 7 94

Acute suppression of spontaneous neurotransmission drives synaptic potentiation.

Nosyreva E, Szabla K, Autry AE, Ryazanov AG, Monteggia LM, Kavalali ET J. Neurosci. 2013 Apr 33 16 6990-7002

Age dependence of the rapid antidepressant and synaptic effects of acute NMDA receptor blockade.

Nosyreva E, Autry AE, Kavalali ET, Monteggia LM. Front Mol Neurosci. 2012 Dec 7 94: 1-6

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses.

Autry AE, Adachi M, Nosyreva E, Na ES, Los MF, Cheng PF, Kavalali ET, Monteggia LM Nature 2011 Jul 475 7354 91-5

Spontaneous neurotransmission: an independent pathway for neuronal signaling?

Kavalali ET, Chung C, Khvotchev M, Leitz J, Nosyreva E, Raingo J, Ramirez DM Physiology (Bethesda) 2011 Feb 26 1 45-53

Activity-dependent augmentation of spontaneous neurotransmission during endoplasmic reticulum stress.

Nosyreva E, Kavalali ET J. Neurosci. 2010 May 30 21 7358-68

Activity-Dependent Augmentation of Spontaneous Neurotransmission during Endoplasmic Reticulum Stress.

. Nosyreva E. D., Kavalali E.T. J. Neurosci. 2010 30 7358-7368

Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the model of fragile x syndrome.

Nosyreva E., Huber K, J. of Neurophysiology 95: 3291-3295. 2006 95 3291-3295

• Department of Neuroscience (2002)