Download Curriculum Vitae

Ngoc Uyen Nhi Nguyen, Ph.D., is an Assistant Instructor in the Department of Internal Medicine at UT Southwestern Medical Center, and a member of its Division of Cardiology.

Originally from Vietnam, Dr. Nguyen holds a bachelor’s degree in medical laboratory science from the University of Medicine and Pharmacy of Ho Chi Minh City in Vietnam. She received a master’s degree in medical laboratory science and biotechnology and a doctorate degree in life sciences from the National Cheng Kung University in Taiwan. In 2016, she joined UTSW as a joint postdoctoral fellow in the labs of Drs. Rothermel and Sadek to conduct cardiac regeneration research. Dr. Nguyen then joined the laboratory of Dr. Sadek as an Assistant Instructor in 2021.

Dr. Nguyen’s research interests include cardiac muscle regeneration, skeletal muscle differentiation, and heart failure.

During her free time, she enjoys cooking, reading, gaming, and spending time with her family.

Research Interest

  • Cardiac and Skeletal Muscle Regeneration
  • Heart Failure
  • Muscular Dystrophy
  • Sarcopenia
  • Skeletal Muscle Differentiation


Featured Publications LegendFeatured Publications

Identification of tetracycline combinations as EphB1 tyrosine kinase inhibitors for treatment of neuropathic pain.
Ahmed MS, Wang P, Nguyen NUN, Nakada Y, Menendez-Montes I, Ismail M, Bachoo R, Henkemeyer M, Sadek HA, Kandil ES, Proc Natl Acad Sci U S A 2021 Mar 118 10
Mechanism of Eccentric Cardiomyocyte Hypertrophy Secondary to Severe Mitral Regurgitation.
Li S, Nguyen NUN, Xiao F, Menendez-Montes I, Nakada Y, Tan WLW, Anene-Nzelu CG, Foo RS, Thet S, Cardoso AC, Wang P, Elhelaly WM, Lam NT, Pereira AHM, Hill JA, Sadek HA, Circulation 2020 Jun 141 22 1787-1799
Mitochondrial Substrate Utilization Regulates Cardiomyocyte Cell Cycle Progression.
Cardoso AC, Lam NT, Savla JJ, Nakada Y, Pereira AHM, Elnwasany A, Menendez-Montes I, Ensley EL, Petric UB, Sharma G, Sherry AD, Malloy CR, Khemtong C, Kinter MT, Tan WLW, Anene-Nzelu CG, Foo RS, Nguyen NUN, Li S, Ahmed MS, Elhelaly WM, Abdisalaam S, Asaithamby A, Xing C, Kanchwala M, Vale G, Eckert KM, Mitsche MA, McDonald JG, Hill JA, Huang L, Shaul PW, Szweda LI, Sadek HA, Nat Metab 2020 Feb 2 2 167-178
Fibroblast Primary Cilia are Required for Cardiac Fibrosis.
Villalobos E, Criollo A, Schiattarella GG, Altamirano F, French KM, May HI, Jiang N, Nguyen NUN, Romero D, Roa JC, García L, Diaz-Araya G, Morselli E, Ferdous A, Conway SJ, Sadek HA, Gillette TG, Lavandero S, Hill JA, Circulation 2019 Mar
DNA Damage Response Mediates Pressure Overload-Induced Cardiomyocyte Hypertrophy.
Nakada Y, Nhi Nguyen NU, Xiao F, Savla JJ, Lam NT, Abdisalaam S, Bhattacharya S, Mukherjee S, Asaithamby A, Gillette TG, Hill JA, Sadek HA Circulation 2019 Feb 139 9 1237-1239
Regulator of Calcineurin 1 helps coordinate whole-body metabolism and thermogenesis.
Rotter D, Peiris H, Grinsfelder DB, Martin AM, Burchfield J, Parra V, Hull C, Morales CR, Jessup CF, Matusica D, Parks BW, Lusis AJ, Nguyen NUN, Oh M, Iyoke I, Jakkampudi T, McMillan DR, Sadek HA, Watt MJ, Gupta RK, Pritchard MA, Keating DJ, Rothermel BA EMBO Rep. 2018 Dec 19 12
Dual roles of palladin protein in in vitro myogenesis: inhibition of early induction but promotion of myotube maturation.
Nguyen NU, Wang HV, PLoS One 2015 10 4 e0124762
Actin-associated protein palladin is required for migration behavior and differentiation potential of C2C12 myoblast cells.
Nguyen NU, Liang VR, Wang HV, Biochem Biophys Res Commun 2014 Sep 452 3 728-33


Featured Books Legend Featured Books

Chapter 8 - Autophagy in germ cells, stem cells, and induced pluripotent stem cells. In Autophagy in Health and Disease

Moydul Islam, Ngoc Uyen Nhi Nguyen, Abhinav Diwan and Beverly A. Rothermel (2022). Elsevier

Honors & Awards

  • American Heart Association
    Career Development Award (2021-2024)
  • The Hamon Center for Regenerative Science and Medicine, UT Southwestern Medical Center
    Trainee Fellowship (2020-2021)
  • American Heart Association
    Postdoctoral Fellowship (2018-2020)
  • The Hamon Center for Regenerative Science and Medicine, UT Southwestern Medical Center
    Trainee Fellowship (2017-2018)
  • The Biology Society of China 38th Conference-Biodiversity Under Threat Symposium, Taiwan
    Best Poster Award (2013)

Professional Associations/Affiliations

  • American Heart Association (2017)